By L. M. King, L. H. Opie (auth.), Salah Abdel-Aleem, James E. Lowe (eds.)
This specific factor of Molecular and mobile Biochemistry includes unique learn papers in addition to invited reports centred within the box of cardiac metabolism and its rules lower than common and affliction stipulations. those papers disguise many components below extensive and quick improvement equivalent to the legislation of fatty acid oxidation within the center, the function of cardiac glycogen in the course of ischemia, the function of CPT I isoenzymes, the pathophysiology of diabetic cardiomyopathy, cardiac defense via rules of power creation, the position of fatty acid binding protein less than common and pathological stipulations, and several very important themes during this zone of analysis. we are hoping that this distinctive factor of Molecular and CellularBiochemistry offers an up to date resource of data for scientists and clinicians attracted to the mechanism during which cardiac metabolism is regulated in health and wellbeing and illness and the mechanistic courting among disturbances in cardiac metabolism and the genesis of cardiovascular diseases.
Read or Download Cardiac Metabolism in Health and Disease PDF
Similar health books
Polycystic Ovary Syndrome is the most typical hormonal sickness between girls of reproductive age, and if left unchecked, is associated with severe future health matters like infertility, sort 2 diabetes, center disorder, and endometrial melanoma. during this groundbreaking e-book, registered dietitian Hillary Wright explains this more and more clinically determined illness and introduces the holistic symptom-management software she built by means of operating with hundreds of thousands of sufferers.
`It has specific allure for health-care pros and executives with an curiosity in company and scientific governance' - British magazine of Perioperative Nursing in recent times the healthiness professions were topic to extraordinary regulatory adjustments. publicity of terrible perform provoked common feedback of self-regulation and demands a approach during which the pursuits of healthiness care shoppers and employers are extra absolutely well-known.
Paintings lodging and Retention in psychological wellbeing and fitness Izabela Z. Schultz and E. Sally Rogers, Editors psychological disorder has lengthy been famous as a reason behind unemployment and diminished task productiveness. extra lately, a myriad of social, criminal, and demographic components have introduced extra individuals with psychological future health impairments into the office, leading to massive sensible questions for employers, rehabilitation experts, and different execs, fairly on lodging and retention matters.
Someday within the Nineteen Eighties, Norbert Singer, the then Director of Thames Polytechnic, got interested within the thought of turning into all in favour of nurse educa tion. venture 2000 have been released. In these days, there have been 3 certified nurses within the Polytechnic: all within the university of submit obligatory schooling and coaching, and all interested by the learning of nurse tutors.
- Natriuretic Peptides in Health and Disease
- Ginkgo Biloba (Storey Country Wisdom Bulletin, A-231)
- The Deadly Ideas of Neoliberalism: How the IMF Has Undermined Public Health and the Fight Against AIDS
- A PROJECTION METHOD FOR PUBLIC HEALTH AND LONG-TERM CARE EXPENDITURES ECONOMICS DEPARTMENT WORKING PAPERS No. 1048
- Free Your Back: Ease Pain and Regain Natural Poise with Gentle Exercise Based on the Alexander Technique
- Mental Health Computing
Additional resources for Cardiac Metabolism in Health and Disease
Molecular cloning techniques have demonstrated that two CPT-I isoforms exist as genes encoding the 'muscle' and 'liver' enzymes. Regulation offatty acid oxidation rates depends on both short-term regulation of enzyme activity and long-term regulation of enzyme synthesis. Most early investigations into metabolic control offatty acid oxidation at the CPT-I step concentrated on the hepatic enzyme which can be inhibited by malonylCoA and can undergo dramatic amplification or reduction of its sensitivity to inhibition by malonyl-CoA.
Cell 83: 841-850, 1995 Park EA, Mynatt RL, Cook GA, Kahfi K: Insulin regulates enzyme activity, malonyl-CoA sensitivity and mRNA abundance of hepatic camitine palmitoyltransferase-l. Biochem J 310: 853-858,1995 Asins G, Serra D, Arias G, Hegardt FG: Developmental changes in camitine palmitoyltransferase I and II genes during development in the rat. Biochem J 306: 379-384, 1995 Hudson EK, Liu MH, Buja LM, McMillin 18: Insulin-associated changes in carnitine palmitoyltransferase in cultured neonatal rat cardiac myocytes.
Biochem J 206: 177-179,1982 15. Cook GA: Differences in the sensitivity of carnitine palmitoyltransferase to inhibition by malonyl-CoA are due to differences in K. values. J Bioi Chern 259: 12030--12033,1984 ' 16. Cook GA, Gamble MS: Regulation of camitine palmitoyltransferase by insulin results in decreased activity and decreased apparent ~ values for malonyl-CoA. J Bioi Chern 262: 2050--2055, 1987 17. Mynatt RL, Greenhaw JJ, Cook GA: Cholate extracts ofmitochondrial oUler membranes increase malonyl-Co A inhibition of caroitine palmitoyltransferase-I by a mechanism involving phospholipids.
Cardiac Metabolism in Health and Disease by L. M. King, L. H. Opie (auth.), Salah Abdel-Aleem, James E. Lowe (eds.)