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ISBN-10: 0470718951

ISBN-13: 9780470718957

ISBN-10: 047072238X

ISBN-13: 9780470722381

Chapter 1 Chairman's starting comments (pages 2–3): W. Feldberg
Chapter 2 Distribution of Histamine within the physique (pages 4–13): W. Feldberg
Chapter three Histamine and Mast Cells (pages 14–19): G.B. West
Chapter four Histamine and Intracellular debris (pages 20–35): F.C. Macintosh
Chapter five unfastened and Conjugated Histamine (pages 36–44): J.H. Gaddum
Chapter 6 brief verbal exchange: Histamine and Mast Cells (pages 45–46): James F. Riley
Chapter 7 brief conversation: motion of 48/80 at the Mast mobile inhabitants and Histamine content material of the Wall of the Gastro?Intestinal Tract of the Rat (pages 47–50): I. Mota, W.T. Beraldo, A.G. Ferri and L.C.U. Junqueira
Chapter eight brief conversation: The Isolation of Imidazoleacetic Acid Riboside (page 51): H. Tabor
Chapter nine brief verbal exchange: Histaminopexig motion of Blood Serum (pages 52–56): Jean?Louis Parrot and Claude Laborde
Chapter 10 brief verbal exchange: Inhibition of Histidine Decarboxylase in vivo via Derivatives of Benzyl?1?Isoquinoline (pages 57–58): Jean?Louis Parrot and Claude Laborde
Chapter eleven The Mechanism of Histamine unencumber (pages 59–73): W. D. M. Paton
Chapter 12 size of Histamine?Releasing job (pages 74–91): J.L. Mongar
Chapter thirteen Histamine unencumber by way of lengthy Chain Molecules (pages 92–123): B.N. Halpern
Chapter 14 Histamine free up via clearly happening ingredients (pages 124–138): M. Rocha and E. Silva
Chapter 15 Histamine free up and Anaphylaxis (pages 139–149): H.O Schild
Chapter sixteen brief communique: Antihistamine medicines and Histamine unlock, in particular in Anaphylaxis (pages 150–154): J.J. Reuse
Chapter 17 brief conversation: free up of Histamine—Clinical issues (pages 155–159): H.O.J. Collier
Chapter 18 brief conversation: the discharge of mobile Histamine in Rabbit Blood via Dextran and Dextran Sulphate (pages 160–166): C.G. Haining
Chapter 19 brief verbal exchange: Histamine free up and the Angio?Oedema kind of response (pages 167–169): M. Schachter
Chapter 20 brief verbal exchange: The Mode of Histamine Binding in Animal Tissues (pages 170–172): Floyd C. McIntire
Chapter 21 brief communique: Endogenous Histamine Liberation in guy (pages 173–174): J. Lecomte
Chapter 22 brief communique: A sluggish Reacting Substance in Anaphylaxis—“SRS?A” (pages 175–179): W.E. Brocklehurst
Chapter 23 brief verbal exchange: a few Discrepancies within the Histamine concept of Anaphylaxis in gentle Muscle (pages 180–182): D.F. Hawkins and L.M. Rosa
Chapter 24 The beginning and destiny of Histamine within the physique (pages 183–188): R.W. Schayer
Chapter 25 Histamine and Gastric Secretion (pages 189–219): Charles F. Code
Chapter 26 Histamine and Vasodilatation (pages 220–234): R.F. Whelan
Chapter 27 Histamine and Nerves (pages 235–241): U.S. von Euler
Chapter 28 dermis Histamine (pages 242–247): W.L.M. Perry
Chapter 29 the importance of Histaminase within the physique (pages 248–257): G. Kahlson
Chapter 30 brief communique: at the category and Nomenclature of Amine Oxidases (pages 258–263): E.A Zeller
Chapter 31 brief conversation: Histamine in Nerves (pages 264–269): E. Werle
Chapter 32 brief conversation: Histamine and Gastric Secretion (pages 270–271): R.A. Gregory
Chapter 33 brief verbal exchange: The impression of intercourse Hormones on Histaminase (pages 272–277): R. Kapeller?Adler
Chapter 34 brief conversation: The motion of Histamine at the Sympathetic anxious method (pages 278–279): Ullrich Trendelenburg
Chapter 35 brief communique: Histamine and the Vasodilator Axon Reflex of the outside (pages 280–281): Jean?Louis Parrot
Chapter 36 brief verbal exchange: Imidazoleacetic acid Metabolism in micro organism (pages 282–283): H. Tabor
Chapter 37 The starting place of Histamine within the physique (pages 284–297): J. H. Gaddum
Chapter 38 The beginning of Histamine within the physique (pages 298–317): R. W. Schayer
Chapter 39 The destiny of Histamine within the physique (pages 318–338): Herbert Tabor
Chapter forty The destiny of Histamine within the physique, with specific connection with the Enzymology of Histamine Oxidation (pages 339–355): E. A. Zeller
Chapter forty-one Is Histaminase exact with Diamine Oxidase? (pages 356–380): R. Kapeller?Adler
Chapter forty two feedback at the place of Histamine in Mammalian Tissues (pages 381–397): H. Blaschko
Chapter forty three the site of Histamine within the physique (pages 398–415): James F. Riley
Chapter forty four The Mechanism of Histamine unlock (pages 416–430): Floyd C. McIntire
Chapter forty five Mechanism of Histamine free up (pages 431–460): Georges Ungar

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There was some evidence of activity since many cells were pleomorphic and some showed perinuclear clear areas in the cytoplasm. I n places, there were even mitoses. This lesion contained no less than 950 pg. histamine per g. tissue-by far the highest histamine content of any human tissue so far recorded by us. As regards pathological tissues from animals, we have now been fortunate in securing more than a dozen dog mast cell tumours, largely through the kindness of Mr. K. W. Head of Edinburgh. I n nearly every case, excellent correlation exists between the histamine values on the one hand, and the mast cell and heparin contents on the other.

B. (1953). J . , 120,528. RILEY,J. B. (1955). J . Path. , 69, 269. 0. E HISTAMINE W. WOLSENHOLMB ond CECILIA M. 4 FOUNDATION HISTAMINE AND INTRACELLULAR PARTICLES F. C. MACINTOSH Department of Physiology, McGill University, Montreal, Canada THE EVIDENCE is now, I think, quite convincing (cf. Riley, 1954)that there is a close association between mast cells and histamine: that these cells are the storehouse for much, perhaps most, of the body’s histamine; that they are particularly vulnerable to certain specialized weapons of chemical assault-antigens in the presence of their antibodies, certain polypeptides, and many basic organic compounds; and that the histamine set free by such agents as these comes mainly from injured or disrupted mast cells.

D. M. (1951). Brit. J . , 6,499. RILEY,J. (1953). J . Path. , 65,471. RILEY,J. (1954). Lancet, 1, 841. RILEY,J. ,and WEST,G. B. (1953). J. , 120, 528. ROCHA E SILVA,M. (1944). J . Allergy, 15,399. ROCHA E SILVA, M. (1954). Quart. Rev. Allergy, 8 , 220. RUBINI,J. , BECKER, R. , and STAHMANN, M. A. (1953). Proc. SOC. exp. , 82, 231. SCHACHTER, M. (1952). Brit. J. , 7,646. SCHNEIDER, W. , and HOGEBOOM, J. H. (1951). , 11, 1. SPECTOR, W. (1953). Proc. roy. ,B,141,268. TRETIIEWIE, E. R. (1938). Aust.

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Ciba Foundation Symposium - Histamine

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